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Pathology Report Structuring Agent

Laboratory & DiagnosticsDiagnostics

Converts free-text pathology reports into structured findings for oncology pathways and tumor boards.

4
Process steps
5
Integrations
4
Data inputs

Pathology reports are rich in clinical detail but often free-text, making it hard to feed oncology pathways, tumor boards, registries, and decision support

Manual abstraction of diagnosis, grade, stage elements, biomarkers, and margins is slow and inconsistent

Downstream teams re-read reports to find key fields, delaying treatment planning

The Pathology Report Structuring Agent converts free-text pathology reports into structured findings so oncology pathways and tumor boards can act on complete, computable data

The agent ingests final pathology reports, extracts and normalizes key diagnostic and biomarker fields using NLP and ontology mapping, validates required elements for cancer pathways, and publishes structured outputs to EHR oncology modules, tumor board packets, and registries.

1

Ingest Pathology Reports

  • Retrieve final and amended surgical pathology and cytology reports
  • Identify report sections (diagnosis, microscopic, synoptic, IHC/molecular)
  • Link reports to specimen, encounter, and oncology episode
Outcome: Report text is organized and ready for structured extraction.
2

Extract Structured Findings

  • Extract primary diagnosis, histology, grade, and laterality
  • Capture margins, lymph nodes, pTNM elements, and specimen adequacy
  • Pull biomarkers and molecular results (e.g., ER/PR/HER2, EGFR, MSI)
Outcome: Core oncology data elements are available as structured fields.
3

Normalize and Validate

  • Map terms to SNOMED, ICD-O, and CAP synoptic standards
  • Validate completeness against cancer pathway and registry requirements
  • Flag ambiguities or missing elements for pathologist review
Outcome: Structured data is standards-aligned and quality-checked.
4

Publish for Pathways and Tumor Boards

  • Write structured findings to EHR oncology and discrete data fields
  • Assemble tumor board summaries with key pathology highlights
  • Feed cancer registry and clinical trial matching workflows
Outcome: Oncology teams receive computable pathology data without manual abstraction.
Epic Beaker
Cerner
CoPath
Epic Beacon
NAACCR Cancer Registry