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Controlled Substance Monitoring Agent

PharmacyDiversion Prevention

Monitors controlled substance dispensing for diversion risk, PDMP signals, and stewardship exceptions.

4
Process steps
5
Integrations
4
Data inputs

Diversion and unsafe controlled-substance use threaten patient safety and organizational compliance

Dispensing, waste, ADC transactions, and PDMP data live in separate systems, making pattern detection slow and retrospective

Stewardship exceptions—high MME, overlapping opioids/benzodiazepines, frequent early refills—are easy to miss at scale

The Controlled Substance Monitoring Agent continuously monitors dispensing for diversion risk, PDMP signals, and stewardship exceptions so pharmacy and compliance teams can intervene early

The agent aggregates controlled-substance dispensing, automated dispensing cabinet activity, waste documentation, and PDMP queries. It scores diversion and misuse risk, flags stewardship exceptions, and routes investigations to pharmacy leadership and compliance with full audit trails.

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Aggregate Controlled Substance Activity

  • Ingest dispensing, ADC pulls, waste, returns, and override events
  • Link transactions to providers, nurses, patients, and locations
  • Pull PDMP query results and external fill signals where available
Outcome: A unified controlled-substance activity feed is ready for analysis.
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Score Diversion and Misuse Risk

  • Detect anomalous user patterns (e.g., waste discrepancies, odd-hour access)
  • Identify patient-level red flags: early refills, multi-provider, high MME
  • Cross-check PDMP signals for multi-pharmacy or cash-pay patterns
Outcome: Risk-ranked diversion and misuse candidates are produced.
3

Flag Stewardship Exceptions

  • Apply opioid stewardship rules (MME thresholds, concurrent benzos, duration)
  • Flag missing PDMP checks where policy requires them
  • Highlight exceptions to formulary and protocol for controlled drugs
Outcome: Stewardship outliers are queued for clinical and compliance review.
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Route Investigations and Document Outcomes

  • Open investigation cases for pharmacy and compliance teams
  • Preserve chain-of-custody evidence and audit logs
  • Track remediation, education, or referral outcomes
Outcome: Diversion and stewardship issues are investigated with complete documentation.
Pyxis
Omnicell
Epic Willow
State PDMP Gateways
Imprivata